ZNF265 Antibody - #AF0753
| 製品: | ZNF265 Antibody |
| カタログ: | AF0753 |
| タンパク質の説明: | Rabbit polyclonal antibody to ZNF265 |
| アプリケーション: | WB IF/ICC |
| 反応性: | Human, Mouse, Rat |
| 予測: | Pig, Bovine, Horse, Sheep, Rabbit, Dog, Chicken |
| 分子量: | 34kDa; 37kD(Calculated). |
| ユニプロット: | O95218 |
| RRID: | AB_2834194 |
製品説明
*The optimal dilutions should be determined by the end user.
*Tips:
WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.
引用形式: Affinity Biosciences Cat# AF0753, RRID:AB_2834194.
折りたたみ／展開
ZRANB 2; DKFZp686J1831; DKFZp686N09117; FLJ41119; OTTHUMP00000011240; OTTHUMP00000011241; Zinc finger protein 265; Zinc finger RAN binding domain containing 2; Zinc finger Ran binding domain containing protein 2; Zinc finger splicing; ZIS; ZIS1; ZIS2; ZNF265;
免疫原
- O95218 ZRAB2_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MSTKNFRVSDGDWICPDKKCGNVNFARRTSCNRCGREKTTEAKMMKAGGTEIGKTLAEKSRGLFSANDWQCKTCSNVNWARRSECNMCNTPKYAKLEERTGYGGGFNERENVEYIEREESDGEYDEFGRKKKKYRGKAVGPASILKEVEDKESEGEEEDEDEDLSKYKLDEDEDEDDADLSKYNLDASEEEDSNKKKSNRRSRSKSRSSHSRSSSRSSSPSSSRSRSRSRSRSSSSSQSRSRSSSRERSRSRGSKSRSSSRSHRGSSSPRKRSYSSSSSSPERNRKRSRSRSSSSGDRKKRRTRSRSPERRHRSSSGSSHSGSRSSSKKK
種類予測
Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.
High(score>80) Medium(80>score>50) Low(score<50) No confidence
PTMs - O95218 基板として
| Site | PTM Type | Enzyme | Source |
|---|---|---|---|
| S9 | Phosphorylation | Uniprot | |
| T50 | Phosphorylation | Uniprot | |
| K54 | Acetylation | Uniprot | |
| K54 | Ubiquitination | Uniprot | |
| K59 | Acetylation | Uniprot | |
| K59 | Ubiquitination | Uniprot | |
| R61 | Methylation | Uniprot | |
| S65 | Phosphorylation | Uniprot | |
| S83 | Phosphorylation | Uniprot | |
| T90 | Phosphorylation | Uniprot | |
| K92 | Acetylation | Uniprot | |
| Y93 | Phosphorylation | Uniprot | |
| K95 | Sumoylation | Uniprot | |
| K95 | Ubiquitination | Uniprot | |
| Y102 | Phosphorylation | Uniprot | |
| Y114 | Phosphorylation | Uniprot | |
| S120 | Phosphorylation | Uniprot | |
| Y124 | Phosphorylation | Uniprot | |
| K137 | Methylation | Uniprot | |
| S143 | Phosphorylation | Uniprot | |
| S153 | Phosphorylation | Uniprot | |
| S165 | Phosphorylation | Uniprot | |
| K168 | Ubiquitination | Uniprot | |
| S181 | Phosphorylation | Uniprot | |
| K182 | Ubiquitination | Uniprot | |
| Y183 | Phosphorylation | Uniprot | |
| S188 | Phosphorylation | Uniprot | |
| S193 | Phosphorylation | Uniprot | |
| S206 | Phosphorylation | Uniprot | |
| S208 | Phosphorylation | Uniprot | |
| S213 | Phosphorylation | Uniprot | |
| S217 | Phosphorylation | Uniprot | |
| S218 | Phosphorylation | Uniprot | |
| S221 | Phosphorylation | Uniprot | |
| S249 | Phosphorylation | Uniprot | |
| S273 | Phosphorylation | Uniprot | |
| S275 | Phosphorylation | Uniprot | |
| S279 | Phosphorylation | Uniprot | |
| S280 | Phosphorylation | Uniprot | |
| S288 | Phosphorylation | Uniprot | |
| S290 | Phosphorylation | Uniprot | |
| T303 | Phosphorylation | Uniprot | |
| S305 | Phosphorylation | Uniprot | |
| S307 | Phosphorylation | Uniprot | |
| S318 | Phosphorylation | Uniprot | |
| S323 | Phosphorylation | Uniprot | |
| S326 | Phosphorylation | Uniprot |
研究背景
Splice factor required for alternative splicing of TRA2B/SFRS10 transcripts. May interfere with constitutive 5'-splice site selection.
Isoform 2 is phosphorylated on Ser-310 upon DNA damage, probably by ATM or ATR.
Nucleus.
Interacts with the C-terminal half of SNRNP70, the Arg/Ser-rich domain of AKAP17A as well as with U2AF1 and CLK1.
The RanBP2-type zinc fingers mediate binding to RNA.
Belongs to the ZRANB2 family.
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