NDUC2 Antibody - #AF0351
| 製品: | NDUC2 Antibody |
| カタログ: | AF0351 |
| タンパク質の説明: | Rabbit polyclonal antibody to NDUC2 |
| アプリケーション: | WB IHC |
| 反応性: | Human, Rat |
| 分子量: | 14kDa; 14kD(Calculated). |
| ユニプロット: | O95298 |
| RRID: | AB_2834196 |
製品説明
*The optimal dilutions should be determined by the end user.
*Tips:
WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.
引用形式: Affinity Biosciences Cat# AF0351, RRID:AB_2834196.
折りたたみ／展開
B14.5b; CI-B14.5b; Complex I B14.5b; Complex I subunit B14.5b; Complex I-B14.5b; HLC-1; HLC1; Human lung cancer oncogene 1 protein; NADH dehydrogenase (ubiquinone) 1, subcomplex unknown, 2, 14.5kDa; NADH dehydrogenase [ubiquinone] 1 subunit C2; NADH dehydrogenase ubiquinone 1 subunit C2; NADH ubiquinone oxidoreductase subunit B14.5b; NADH-ubiquinone oxidoreductase subunit B14.5b; NADHDH2; NDUC2_HUMAN; NDUFC2;
免疫原
A synthesized peptide derived from human NDUC2, corresponding to a region within C-terminal amino acids.
- O95298 NDUC2_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MIARRNPEPLRFLPDEARSLPPPKLTDPRLLYIGFLGYCSGLIDNLIRRRPIATAGLHRQLLYITAFFFAGYYLVKREDYLYAVRDREMFGYMKLHPEDFPEEDKKTYGEIFEKFHPIR
PTMs - O95298 基板として
| Site | PTM Type | Enzyme | Source |
|---|---|---|---|
| S19 | Phosphorylation | Uniprot | |
| T54 | Phosphorylation | Uniprot | |
| Y80 | Phosphorylation | Uniprot | |
| K94 | Ubiquitination | Uniprot | |
| K105 | Ubiquitination | Uniprot | |
| K106 | Ubiquitination | Uniprot | |
| K114 | Acetylation | Uniprot | |
| K114 | Sumoylation | Uniprot | |
| K114 | Ubiquitination | Uniprot |
研究背景
Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.
Mitochondrion inner membrane>Single-pass membrane protein>Matrix side.
Complex I is composed of 45 different subunits.
Belongs to the complex I NDUFC2 subunit family.
研究領域
· Human Diseases > Endocrine and metabolic diseases > Non-alcoholic fatty liver disease (NAFLD).
· Human Diseases > Neurodegenerative diseases > Alzheimer's disease.
· Human Diseases > Neurodegenerative diseases > Parkinson's disease.
· Human Diseases > Neurodegenerative diseases > Huntington's disease.
· Metabolism > Energy metabolism > Oxidative phosphorylation.
· Metabolism > Global and overview maps > Metabolic pathways.
· Organismal Systems > Nervous system > Retrograde endocannabinoid signaling. (View pathway)
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