EGR2 Antibody - #AF0480
(3)
(4)
| 製品: | EGR2 Antibody |
| カタログ: | AF0480 |
| タンパク質の説明: | Rabbit polyclonal antibody to EGR2 |
| アプリケーション: | WB IHC |
| 反応性: | Human, Mouse, Rat |
| 予測: | Pig, Horse, Sheep, Rabbit, Dog, Xenopus |
| 分子量: | 50kDa; 50kD(Calculated). |
| ユニプロット: | P11161 |
| RRID: | AB_2834210 |
製品説明
*The optimal dilutions should be determined by the end user.
*Tips:
WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.
引用形式: Affinity Biosciences Cat# AF0480, RRID:AB_2834210.
折りたたみ／展開
AT225; AT591; CMT1D; CMT4E; E3 SUMO-protein ligase EGR2; Early growth response 1; Early growth response 2; Early growth response protein 1; Early growth response protein 2; EGR1; EGR2; G0S30; KROX-24; KROX20; Nerve growth factor-induced protein A; NGFI A; NGFI-A; TIS8; Transcription factor ETR103; Transcription factor Zif268; ZIF-268; Zinc finger protein 225; Zinc finger protein Krox-20; Zinc finger protein Krox-24; ZNF225;
免疫原
- P11161 EGR2_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MMTAKAVDKIPVTLSGFVHQLSDNIYPVEDLAATSVTIFPNAELGGPFDQMNGVAGDGMINIDMTGEKRSLDLPYPSSFAPVSAPRNQTFTYMGKFSIDPQYPGASCYPEGIINIVSAGILQGVTSPASTTASSSVTSASPNPLATGPLGVCTMSQTQPDLDHLYSPPPPPPPYSGCAGDLYQDPSAFLSAATTSTSSSLAYPPPPSYPSPKPATDPGLFPMIPDYPGFFPSQCQRDLHGTAGPDRKPFPCPLDTLRVPPPLTPLSTIRNFTLGGPSAGVTGPGASGGSEGPRLPGSSSAAAAAAAAAAYNPHHLPLRPILRPRKYPNRPSKTPVHERPYPCPAEGCDRRFSRSDELTRHIRIHTGHKPFQCRICMRNFSRSDHLTTHIRTHTGEKPFACDYCGRKFARSDERKRHTKIHLRQKERKSSAPSASVPAPSTASCSGGVQPGGTLCSSNSSSLGGGPLAPCSSRTRTP
種類予測
Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.
High(score>80) Medium(80>score>50) Low(score<50) No confidence
PTMs - P11161 基板として
| Site | PTM Type | Enzyme | Source |
|---|---|---|---|
| S70 | Phosphorylation | Uniprot | |
| Y75 | Phosphorylation | Uniprot | |
| S77 | Phosphorylation | Uniprot | |
| R257 | Methylation | Uniprot | |
| T263 | Phosphorylation | Uniprot | |
| R293 | Methylation | Uniprot | |
| T391 | Phosphorylation | Uniprot | |
| T393 | Phosphorylation | Uniprot |
研究背景
Sequence-specific DNA-binding transcription factor. Binds to two specific DNA sites located in the promoter region of HOXA4.
E3 SUMO-protein ligase helping SUMO1 conjugation to its coregulators NAB1 and NAB2, whose sumoylation down-regulates EGR2 own transcriptional activity.
Ubiquitinated by WWP2 leading to proteasomal degradation.
Nucleus.
Interacts with HCFC1. Interacts with WWP2. Interacts with UBC9.
Belongs to the EGR C2H2-type zinc-finger protein family.
研究領域
· Human Diseases > Infectious diseases: Viral > Hepatitis B.
· Human Diseases > Infectious diseases: Viral > HTLV-I infection.
· Human Diseases > Cancers: Overview > Viral carcinogenesis.
参考文献
Application: WB Species: rat Sample: BMSCs
Restrictive clause
Affinity Biosciences tests all products strictly. Citations are provided as a resource for additional applications that have not been validated by Affinity Biosciences. Please choose the appropriate format for each application and consult Materials and Methods sections for additional details about the use of any product in these publications.
For Research Use Only.
Not for use in diagnostic or therapeutic procedures. Not for resale. Not for distribution without written consent. Affinity Biosciences will not be held responsible for patent infringement or other violations that may occur with the use of our products. Affinity Biosciences, Affinity Biosciences Logo and all other trademarks are the property of Affinity Biosciences LTD.