ELF1 Antibody - #AF0483
| 製品: | ELF1 Antibody |
| カタログ: | AF0483 |
| タンパク質の説明: | Rabbit polyclonal antibody to ELF1 |
| アプリケーション: | WB IF/ICC |
| 反応性: | Human |
| 予測: | Horse |
| 分子量: | 67kDa; 67kD(Calculated). |
| ユニプロット: | P32519 |
| RRID: | AB_2834232 |
製品説明
*The optimal dilutions should be determined by the end user.
*Tips:
WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.
引用形式: Affinity Biosciences Cat# AF0483, RRID:AB_2834232.
折りたたみ／展開
E74 like factor 1; E74-like factor 1; ELF 1; ELF1; ELF1_HUMAN; Ets domain transcription factor; ETS related transcription factor Elf 1; ETS related transcription factor Elf1; ets-related transcription factor; ETS-related transcription factor Elf-1; mElf 1; p70; Sts1; TRANSCRIPTION FACTOR ELF 1;
免疫原
In fetal tissues, it is highly expressed in heart, lung liver and kidney, and weakly expressed in brain. In adult, it is highly expressed in pancreas, spleen, thymus and peripheral blood leukocytes, expressed at moderate levels in heart, placenta, lung, liver, skeletal muscle, kidney, prostate, ovary, small intestine and colon, and weakly expressed in brain and testis.
- P32519 ELF1_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MAAVVQQNDLVFEFASNVMEDERQLGDPAIFPAVIVEHVPGADILNSYAGLACVEEPNDMITESSLDVAEEEIIDDDDDDITLTVEASCHDGDETIETIEAAEALLNMDSPGPMLDEKRINNNIFSSPEDDMVVAPVTHVSVTLDGIPEVMETQQVQEKYADSPGASSPEQPKRKKGRKTKPPRPDSPATTPNISVKKKNKDGKGNTIYLWEFLLALLQDKATCPKYIKWTQREKGIFKLVDSKAVSRLWGKHKNKPDMNYETMGRALRYYYQRGILAKVEGQRLVYQFKEMPKDLIYINDEDPSSSIESSDPSLSSSATSNRNQTSRSRVSSSPGVKGGATTVLKPGNSKAAKPKDPVEVAQPSEVLRTVQPTQSPYPTQLFRTVHVVQPVQAVPEGEAARTSTMQDETLNSSVQSIRTIQAPTQVPVVVSPRNQQLHTVTLQTVPLTTVIASTDPSAGTGSQKFILQAIPSSQPMTVLKENVMLQSQKAGSPPSIVLGPAQVQQVLTSNVQTICNGTVSVASSPSFSATAPVVTFSPRSSQLVAHPPGTVITSVIKTQETKTLTQEVEKKESEDHLKENTEKTEQQPQPYVMVVSSSNGFTSQVAMKQNELLEPNSF
種類予測
Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.
High(score>80) Medium(80>score>50) Low(score<50) No confidence
PTMs - P32519 基板として
| Site | PTM Type | Enzyme | Source |
|---|---|---|---|
| S110 | Phosphorylation | Uniprot | |
| Y160 | Phosphorylation | Uniprot | |
| S163 | Phosphorylation | Uniprot | |
| S167 | Phosphorylation | Uniprot | |
| S168 | Phosphorylation | Uniprot | |
| T180 | Phosphorylation | Uniprot | |
| S187 | Phosphorylation | Uniprot | |
| T190 | Phosphorylation | Uniprot | |
| T191 | Phosphorylation | Uniprot | |
| S195 | Phosphorylation | Uniprot | |
| K197 | Ubiquitination | Uniprot | |
| K226 | Ubiquitination | Uniprot | |
| K229 | Ubiquitination | Uniprot | |
| T231 | Phosphorylation | Uniprot | |
| K239 | Ubiquitination | Uniprot | |
| K244 | Ubiquitination | Uniprot | |
| K256 | Ubiquitination | Uniprot | |
| Y261 | Phosphorylation | Uniprot | |
| R269 | Methylation | Uniprot | |
| Y271 | Phosphorylation | Uniprot | |
| Y272 | Phosphorylation | Uniprot | |
| K279 | Sumoylation | Uniprot | |
| K279 | Ubiquitination | Uniprot | |
| K290 | Ubiquitination | Uniprot | |
| S332 | Phosphorylation | Uniprot | |
| S333 | Phosphorylation | Uniprot | |
| S334 | Phosphorylation | Uniprot | |
| K346 | Acetylation | Uniprot | |
| S350 | Phosphorylation | Uniprot | |
| S376 | Phosphorylation | Uniprot | |
| S432 | Phosphorylation | Uniprot | |
| S474 | Phosphorylation | Uniprot | |
| K481 | Ubiquitination | Uniprot | |
| T559 | Phosphorylation | Uniprot | |
| T566 | Phosphorylation | Uniprot | |
| K571 | Ubiquitination | Uniprot | |
| S618 | Phosphorylation | Uniprot |
研究背景
Transcription factor that activates the LYN and BLK promoters. Appears to be required for the T-cell-receptor-mediated trans activation of HIV-2 gene expression. Binds specifically to two purine-rich motifs in the HIV-2 enhancer.
Nucleus.
In fetal tissues, it is highly expressed in heart, lung liver and kidney, and weakly expressed in brain. In adult, it is highly expressed in pancreas, spleen, thymus and peripheral blood leukocytes, expressed at moderate levels in heart, placenta, lung, liver, skeletal muscle, kidney, prostate, ovary, small intestine and colon, and weakly expressed in brain and testis.
Binds to the underphosphorylated form of RB. May interact with other transcription factors in order to regulate specific genes. Interacts with RUNX1.
Belongs to the ETS family.
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